Ÿ Jmol‚ÅŒ©‚éƒgƒsƒbƒNƒX•ŖŽqi24-3j Ÿ

Ø No.1-10 b 11-20 b 151-200 b 401-410 b 411-420iģ¬’†j b 421-430 b 431-440 b 441-450 b 451-460 b 461-470 b 471-480 b 481-490 b 491-500 ©
Ø No.501-510 b 511-520 b 521-530 b 531-540 b 541-550 b 551-560 b 561-570 b 571-580 b 581-590 b 591-600 ©
Ø 601-610 b 611-620 b 621-630 b 631-640 b 641-650 b 651-660 b 661-670 b 671-680 b 681-690 b 691-700 ©
Ø 701-710 b 711-720 b 721-730 b 731-740 b 741-750 b 751-760 b 761-770 b 771-780 b 781-790 b 791-800 ©
Ø 801-810 b 811-820 b 821-830 b 831-840 b 841-850 b 851-860 b 861-870 b 871-880 b 861-870 b 881-890 b 891-900 ©
Ø 901-910 b 911-920 b 921-930 b 931-940 b 941-950 b 951-960 b 961-970 b 971-980 b 981-990 b 991-1000 ©
Ø 1001-1010 b 1011-1020 b 1021-1030 b 1031-1040 b 1041-1050 b 1051-1060 b 1061-1070 b 1071-1080 b 1081-1090 b 1091-1100 ©
Ø 1101-1110 b 1111-1120 b 1121-1130 b 1131-1140 b 1141-1150 b 1151-1160 b 1161-1170 ©
Ø ˆČ‰ŗ‚Ķ”Œć‰ü•ĻF Vol.1 b 2 b 3 b 5 b 6 b 7 b 8 a ƒf[ƒ^–¼ˆź—— ©
Ø Å‹ß‚Ģ–{ƒTƒCƒgƒRƒ“ƒeƒ“ƒc‚©‚ēF VŒ^ƒRƒƒiƒEƒCƒ‹ƒXiSARS-CoV-2bCOVID-19jī•ń b ģćƒ‚ƒfƒ‹uŒ®‚ĘŒ®ŒŠv–ĶŒ^ b Œ³‘fE•ŖŽq‚Ŗ“oź‚·‚é–{‚š“Ē‚ą‚¤I ©

ecosci.jpƒTƒCƒg“ą‚Å‚Ķ•Ŗ—Ž‚µ‚É‚­‚¢ƒjƒ…[ƒX‚Č•ŖŽq‚āCRCSB PDB‚ĢV‹KŒöŠJƒf[ƒ^‚Č‚Ē‚š–¬—‚Č‚­ŒfŚ‚µ‚Ü‚·B
¦Jmol•\Ž¦§ŒĄ‚Ģ‚½‚߁C10Œ‚ø‚Ā•\Ž¦‚·‚é‚ꂤ‚É•ĻX‚µ‚Ü‚µ‚½ić‹L‘ŒÉ‚ą‡ŽŸC³‚µ‚Ü‚·jB
¦‹Œ”Å‚Å•\Ž¦‚µ‚Ä‚¢‚½ˆź•”‚ĢŽQlƒf[ƒ^iPDBsum‚Č‚Ēj‚Ķ”Œć’Ē‰Į‚µ‚Ü‚·B
¦–{ƒy[ƒW‚Ģ•ŖŽqƒ‚ƒfƒ‹‚ĶInternet Explorer‚ÅŽQĘ‚Å‚«‚Ü‚·BMicrosoft Edge‚Å‚ĶInternet Explorerƒ‚[ƒh‚É‚µ‚āB
¦PDBsumƒf[ƒ^‚Ńtƒ@ƒCƒ‹–¼*_lp‚Å‚ ‚é‚ą‚Ģ‚ĶLigPlot+ v.2.2‚ÅŽę“¾‚µ‚½‚ą‚Ģ‚Å‚·B
š‹ŒJmolƒgƒsƒbƒN‚Ö‚Ģ’Ē‹L@Ø No.571iŠĀ‹«ƒzƒ‹ƒ‚ƒ“j b No.979iƒJƒvƒTƒCƒVƒ“Žó—e‘Ģj b No.1046iƒfƒB[ƒ‹ƒXEƒAƒ‹ƒhƒ‰[ƒ[j


  1. Structural basis for membrane attack complex inhibition by CD59iNature CommunicationsC2023/02/16j [NEW!]@¦2023/02/22ŒöŠJPDBƒf[ƒ^8b0fi‰ŗŒfjE8b0gE8b0h

    C5b8-CD59ƒRƒ“ƒvƒŒƒbƒNƒX 8b0f‚ĢChain B-GiC5b8‚Ķœ‚­GmmCIF Ø PDB converter‚ÅcifØpdbƒf[ƒ^•ĻŠ·‚µ‚½Œć‰ĮHj
    ƒoƒbƒNƒ{[ƒ“@“ńŽŸ\‘¢
    ‘S‘I‘š@ƒ^ƒ“ƒpƒNŽæ‘I‘š@ƒŠƒKƒ“ƒh‘I‘š@HB‘I‘ši$ˆó‚Ģ‚Żj
    ‹óŠŌ[“U@‹…–_@‹…60“@ƒXƒeƒBƒbƒN@j‹ą@Į‹Ž
    ƒAƒ~ƒmF@ChainF@CPKF@a@JmolF@RasmolF

    “œ½•Ź’…Fi#ˆó‚Ģ‚ŻjFGalCƒæ-GlcCƒĄ-GlcCManCFucCXylCSiaCGalNAcCGlcNAcCGlcA
    Ž_«E’†«E‰–Šī«‹ę•Ź@‹É«E”ń‹É«‹ę•Ź
    ‘a…«ƒCƒ“ƒfƒbƒNƒX‡@I/O’l‡i“Į«Šī Rj@“™“d“_‡
    ƒRƒ“ƒzƒ[ƒVƒ‡ƒ“‘I‘š«iƒæƒwƒŠƒbƒNƒXEƒĄƒXƒgƒ‰ƒ“ƒhj
    …‘fŒ‹‡•\Ž¦
    @
    @@
    ”wŒiE•@ŠD@”’@®


    C5b8-CD59ƒRƒ“ƒvƒŒƒbƒNƒX8b0f‚ĢChain B-GiC5b8‚Ķœ‚­GcifØpdbƒf[ƒ^•ĻŠ·‚µ‚½Œć‰ĮHj


      œƒAƒ~ƒmF•\Ž¦‚Ģ–}—į
      ASP@GLU@CYS@MET@LYS@ARG@SER@THR@PHE@TYR@ASN@GLN@GLY@LEU@VAL@ILE@ALA@TRP@HIS@PRO
      œŽ_«E’†«q–F‘°rE‰–Šī«ƒAƒ~ƒmŽ_‹ę•Ź•\Ž¦‚Ģ–}—į
      ASP@GLU@GLY@ALA@VAL@LEU@ILE@CYS@SER@THR@ASN@GLN@PRO@MET@PHE@TYR@TRP@LYS@ARG@HIS
      œ‹É«qŽ_«E‰–Šī«rE”ń‹É«i‘a…«jƒAƒ~ƒmŽ_‹ę•Ź
      SER@THR@TYR@CYS@ASN@GLN@ASP@GLU@LYS@ARG@HIS@GLY@ALA@VAL@LEU@ILE@PHE@PRO@MET@TRP
      œ‘a…«ƒCƒ“ƒfƒbƒNƒX‡
      ARG@LYS@ASN@ASP@GLN@GLU@HIS@PRO@TYR@TRP@SER@THR@GLY@ALA@MET@CYS@PHE@LEU@VAL@ILE
      œ—L‹@ŠT”O}I/O’l‡i“Į«Šī Rj
      ASN@SER@ASP@GLN@GLU@THR@ARG@HIS@GLY@LYS@TYR@TRP@CYS@MET@PRO@PHE@ALA@VAL@LEU@ILE
      œ“™“d“_‡
      ASP@GLU@CYS@ASN@PHE@GLN@TYR@SER@MET@TRP@VAL@GLY@LEU@ALA@ILE@THR@PRO@HIS@LYS@ARG


    ƒAƒ~ƒmŽ_‚Ø‚ę‚Ń“Į«Šī‚Ģe…«E‘a…« b Log P‚šƒ|ƒPƒbƒg‚ɁI


  2. ”ŒŽ‚Ģ•ŖŽq 279:ŒćŠś‘£i•”‡‘Ģ/ƒTƒCƒNƒƒ\[ƒ€iAnaphase-Promoting Complex / CyclosomejiPDBjC2023/03j [NEW!] b Molecule of the MonthiPDBj@¦u”ŒŽ‚Ģ•ŖŽq 276v‚ĶJmolƒgƒsƒbƒNNo.1156‚É

    APC-Cdc20-Hsl1•”‡‘Ģ5g04‚ĢChain RESiƒAƒ_ƒvƒ^[ƒ^ƒ“ƒpƒNŽæCdc20‚ĘƒfƒOƒƒ“ƒyƒvƒ`ƒh‚Ģ‚Żj
    mAnaphase-promoting complex - WikipediaCDegron - Wikipedian
    5g04‚ĢChain RESiAPC-Cdc20-Hsl1•”‡‘Ģ’†‚ĢƒAƒ_ƒvƒ^[ƒ^ƒ“ƒpƒNŽæCdc20‚ĘƒfƒOƒƒ“ƒyƒvƒ`ƒhj@Chain SiƒfƒOƒƒ“j‘I‘š

    ƒoƒbƒNƒ{[ƒ“@“ńŽŸ\‘¢
    ‘S‘I‘š@ƒ^ƒ“ƒpƒNŽæ‘I‘š@ƒŠƒKƒ“ƒh‘I‘š@HB‘I‘ši$ˆó‚Ģ‚Żj
    ‹óŠŌ[“U@‹…–_@‹…60“@ƒXƒeƒBƒbƒN@j‹ą@Į‹Ž
    ƒAƒ~ƒmF@ChainF@CPKF@a@JmolF@RasmolF

    Ž_«E’†«E‰–Šī«‹ę•Ź@‹É«E”ń‹É«‹ę•Ź
    ‘a…«ƒCƒ“ƒfƒbƒNƒX‡@I/O’l‡i“Į«Šī Rj@“™“d“_‡
    ƒRƒ“ƒzƒ[ƒVƒ‡ƒ“‘I‘š«iƒæƒwƒŠƒbƒNƒXEƒĄƒXƒgƒ‰ƒ“ƒhj
    …‘fŒ‹‡•\Ž¦
    @
    @@
    ”wŒiE•@ŠD@”’@®


    APC-Cdc20-Hsl1•”‡‘Ģ’†‚ĢƒAƒ_ƒvƒ^[ƒ^ƒ“ƒpƒNŽæCdc20‚ĘƒfƒOƒƒ“idegronjƒyƒvƒ`ƒh5g04‚ĢChain RES


  3. ‘ŠŠ‰īF “Į•Ź“Wu“ŁvŒöŽ®}˜^ - ƒtƒWƒeƒŒƒre!ƒVƒ‡ƒbƒv(2022)

    ƒAƒRƒjƒ`ƒ“iaconitinej
    ƒoƒbƒNƒ{[ƒ“@“ńŽŸ\‘¢@@DNA/RNAiATGCUCbackbonej
    ‘S‘I‘š@ƒ^ƒ“ƒpƒNŽæ‘I‘š@ƒŠƒKƒ“ƒh‘I‘š@HB‘I‘ši$ˆó‚Ģ‚Żj@DNA/RNA‘I‘š@DNA/RNA backbone‘I‘š
    ‹óŠŌ[“U@‹…–_@‹…60“@ƒXƒeƒBƒbƒN@j‹ą@Į‹Ž
    ƒAƒ~ƒmF@ChainF@CPKF@a@JmolF@RasmolF

    Ž_«E’†«E‰–Šī«‹ę•Ź@‹É«E”ń‹É«‹ę•Ź
    ‘a…«ƒCƒ“ƒfƒbƒNƒX‡@I/O’l‡i“Į«Šī Rj@“™“d“_‡
    ƒRƒ“ƒzƒ[ƒVƒ‡ƒ“‘I‘š«iƒæƒwƒŠƒbƒNƒXEƒĄƒXƒgƒ‰ƒ“ƒhj
    …‘fŒ‹‡•\Ž¦
    @
    @@
    ”wŒiE•@ŠD@”’@®
    p.13E51‚Ł‚©@DDTFp,p'-DDT@o,p'-DDT@Ø ŠĀ‹«ƒzƒ‹ƒ‚ƒ“‚Ę‚µ‚Ä‹^‚ķ‚ź‚Ä‚¢‚鉻‡•Ø
    p.13@ƒAƒ‹ƒR[ƒ‹FƒGƒ^ƒm[ƒ‹iethanolj@Ø ƒAƒ‹ƒR[ƒ‹‚ĘƒtƒFƒm[ƒ‹
    p.13@ƒJƒtƒFƒCƒ“FƒJƒtƒFƒCƒ“icaffeinej
    p.13@ƒjƒRƒ`ƒ“FƒjƒRƒ`ƒ“inicotinej@Ø •ŖŽq‚Ģ‰ČŠwi‘ę13Ķj
    p.13@“ńŽ_‰»’Y‘fF“ńŽ_‰»’Y‘ficarbon dioxidej@Ø •ŖŽq‚ĢŒ`‚ʐ«Žæ
    p.14@ƒLƒVƒŠƒg[ƒ‹FƒLƒVƒŠƒg[ƒ‹ixylitolj@Ø ŠĆ–”•ØŽæ‚Ģ”é–§
    p.15@ƒtƒBƒuƒŠƒmƒQƒ“F1ltj‚ĢChain ACBCCCGCHiƒtƒBƒuƒŠƒmƒQƒ“ƒ^ƒ“ƒpƒNŽæ‚Ģƒtƒ‰ƒOƒƒ“ƒgD‚Ģ•”•Ŗ\‘¢—įj
    p.16@ƒAƒZƒ`ƒ‹ƒRƒŠƒ“FƒAƒZƒ`ƒ‹ƒRƒŠƒ“iacetylcholineCAChj@Ø R‚¤‚ĀÜ‚ʐ_Œo“`’B•ØŽæ
    p.17E44E100E173‚Ł‚©@ƒeƒgƒƒhƒgƒLƒVƒ“FƒeƒgƒƒhƒgƒLƒVƒ“itetrodotoxinCTTXj@Ø •ŹƒgƒsƒbƒN
    p.17E23@ƒ}ƒCƒgƒgƒLƒVƒ“Fƒ}ƒCƒgƒgƒLƒVƒ“imaitotoxinj a ŽQlF 6j8jiƒeƒgƒƒhƒgƒLƒVƒ“‚ŖŒ‹‡‚µ‚½“dˆŹˆĖ‘¶«ƒiƒgƒŠƒEƒ€ƒ`ƒƒƒlƒ‹j@9SRiƒeƒgƒƒhƒgƒLƒVƒ“j‘I‘š@“ÆPDBsumƒf[ƒ^ 6j8j_9SR$@Ø •ŹƒgƒsƒbƒN
    p.17‚Ł‚©@DNAERNAFiˆČ‰ŗ‚ĶDNAERNA•”•Ŗ\‘¢—įj@Ø DNA‚ĘRNA‚Ģ‚¢‚ė‚¢‚ė‚ČŽp
    1gt0‚ĢChain AEBiOct4ESox2EDNA •”‡‘ĢGDNA‚Ģ‚Żj b 1gt0‘S‘Ģ*@C½iOct1j‘I‘š@D½iSox2j‘I‘š@Ø Oct1/Sox2/DNA •”‡‘Ģ
    1g59‚ĢChain BitRNA\‘¢—įGtRNAGluj@“ÆChain AEBitRNAGlu‚ĘGluRS‚Ģ•”‡‘Ģj
    p.17@ƒƒbƒZƒ“ƒWƒƒ[RNAimRNAjFmRNA•”•Ŗ\‘¢—įiUUUUUUUUUUUUj@Ø ƒRƒhƒ“‚Ęˆā“`ˆĆ†•\
    p.18@RNAƒ|ƒŠƒƒ‰[ƒ[IIF6j4yiDNA/RNA‚ŖŒ‹‡‚µ‚½RNAƒ|ƒŠƒƒ‰[ƒ[IIj@Ø •ŹƒgƒsƒbƒN
    p.18@ƒ}ƒXƒ^[ƒhƒKƒXFƒ}ƒXƒ^[ƒhƒKƒXimustard gasG—°‰»ƒWƒNƒƒƒWƒGƒ`ƒ‹CƒCƒyƒŠƒbƒgj@Ø ’n‰ŗ“SƒTƒŠƒ“Ž–Œ
    p.23‚Ł‚©@ƒAƒ‹ƒJƒƒCƒhF@Ø ƒAƒ‹ƒJƒƒCƒh - ’‚‘f‚©‚ēŒ©‚鐶–½‚Ģ¢ŠE
    p.23‚Ł‚©@ƒqƒXƒ^ƒ~ƒ“FƒqƒXƒ^ƒ~ƒ“ihistaminej@Ø •ŹƒgƒsƒbƒN
    p.24Ep.174‚Ł‚©@ƒAƒRƒjƒ`ƒ“FƒAƒRƒjƒ`ƒ“iaconitinej@Ø ƒAƒ‹ƒJƒƒCƒh - ’‚‘f‚©‚ēŒ©‚鐶–½‚Ģ¢ŠE
    p.26@ƒXƒgƒŠƒLƒj[ƒlFƒXƒgƒŠƒLƒj[ƒlistrychninej@Ø •ŹƒgƒsƒbƒN
    p.26@ƒRƒ‹ƒqƒ`ƒ“FƒRƒ‹ƒqƒ`ƒ“icolchicinej@Ø •ŹƒgƒsƒbƒN
    p.29@ƒ\ƒ‰ƒjƒ“Fƒ\ƒ‰ƒjƒ“isolaninej@Ø •ŹƒgƒsƒbƒN
    p.37@ƒTƒ\ƒŠ‚Ģ“ŁF@Ø •ŹƒgƒsƒbƒNiƒTƒ\ƒŠ“Å—įƒJƒŠƒuƒhƒgƒLƒVƒ“qcharybdotoxinCChTxrj
    p.41@ƒZƒƒgƒjƒ“FƒZƒƒgƒjƒ“iserotoninj@Ø R‚¤‚ĀÜ‚ʐ_Œo“`’B•ØŽæ
    p.46@“Ńwƒr‚Ģ“ŁF@Ø •ŹƒgƒsƒbƒN
    p.48@ƒoƒgƒ‰ƒRƒgƒLƒVƒ“Fƒoƒgƒ‰ƒRƒgƒLƒVƒ“ibatrachotoxinCBTXj@Ø •ŹƒgƒsƒbƒN
    p.49@ƒTƒ}ƒ“ƒ_ƒŠƒ“FƒTƒ}ƒ“ƒ_ƒŠƒ“isamandarinCsamandarinej
    p.52@ƒJƒ“ƒ^ƒŠƒWƒ“FƒJƒ“ƒ^ƒŠƒWƒ“icantharidinj
    p.52@ƒzƒ‚ƒoƒgƒ‰ƒRƒgƒLƒVƒ“Fƒzƒ‚ƒoƒgƒ‰ƒRƒgƒLƒVƒ“ihomobatrachotoxinj
    p.55@ƒÖ-ƒRƒmƒgƒLƒVƒ“ MVIIAF1omg‚ĢModel 1iƒÖ-ƒRƒmƒgƒLƒVƒ“ MVIIAj
    p.57@ƒIƒjƒ_ƒ‹ƒ}ƒIƒRƒ[‚Ģ“ŁF4wvmiƒIƒjƒ_ƒ‹ƒ}ƒIƒRƒ[‚Ģ“Ő¬•ŖƒXƒgƒiƒXƒgƒLƒVƒ“qstonustoxinCSNTXrj@¦PNAS˜_•¶Fig. 2‚É”wž™‚ĢŽŹ^‚ ‚č@Ø •ŹƒgƒsƒbƒN
    p.60@ƒAƒtƒ‰ƒgƒLƒVƒ“B1FƒAƒtƒ‰ƒgƒLƒVƒ“B1iaflatoxin B1j b1ag5‚Ģ•”•Ŗ\‘¢iƒAƒtƒ‰ƒgƒLƒVƒ“B1‘ćŽÓ•Ø‚ĢDNA‚Ö‚ĢCüj@AFNiƒAƒtƒ‰ƒgƒLƒVƒ“B1‘ćŽÓ•Øj‘I‘š @Ø DNA‚ĢĘŽć«‚Ę‹­x«
    p.61@ƒfƒIƒLƒVƒjƒoƒŒƒm[ƒ‹FƒfƒIƒLƒVƒjƒoƒŒƒm[ƒ‹ideoxynivalenolj b “Æ•ŖŽqŒ‹‡PDBsumƒf[ƒ^—į3b2s_B2SiŌƒJƒr•a‹Ū‚Ģ3-O-ƒAƒZƒ`ƒ‹ƒgƒ‰ƒ“ƒXƒtƒFƒ‰[ƒ[j$
    p.63@ƒCƒ{ƒeƒ“Ž_FƒCƒ{ƒeƒ“Ž_iibotenic acidj@Ø •ŹƒgƒsƒbƒN
    p.63@ƒ€ƒVƒ‚[ƒ‹Fƒ€ƒVƒ‚[ƒ‹imuscimolj
    p.63@ƒ€ƒXƒJƒŠƒ“Fƒ€ƒXƒJƒŠƒ“imuscarinej
    p.65@ƒVƒƒVƒrƒ“FƒVƒƒVƒrƒ“iƒTƒCƒƒVƒrƒ“CpsilocybinGpsylocybinj@Ø ŠėŒÆƒhƒ‰ƒbƒO
    p.65@ƒVƒƒVƒ“FƒVƒƒVƒ“iƒTƒCƒƒVƒ“Cpsilocinqpsilocynrj
    p.66@ƒRƒvƒŠƒ“FƒRƒvƒŠƒ“icoprinej
    p.67@ƒAƒ}ƒgƒLƒVƒ“—ŽFƒæ-ƒAƒ}ƒjƒ`ƒ“iƒæ-amanitinGƒAƒ}ƒgƒLƒVƒ“—Ž‚Ģ—įj a ŽQlF 6exv‚ĢChain AEMENEPETiƒæ-ƒAƒ}ƒjƒ`ƒ“‚ŖŒ‹‡‚µ‚½RNAƒ|ƒŠƒƒ‰[ƒ[IIj@Chain Miƒæ-ƒAƒ}ƒjƒ`ƒ“j‘I‘š@“ÆPDBsumƒf[ƒ^6exv_ILX-TRX-GLY-ILE-GLY-CSX-ASN-HYP$ p.71@ƒƒ`ƒ‹…‹āF‰–‰»ƒƒ`ƒ‹…‹āimethylmercury chloridej@Ø …–“•ab …‹āHg‚šŠÜ‚Ž¶‘Ģ•ŖŽq‚ĢSITE—į
    p.73@l‘Ģ‚š\¬‚·‚錳‘fF@Ø ¶‘Ģ•ŖŽq‚Ģ\¬Œ³‘f
    p.74E88‚Ł‚©@—°‰»…‘fF—°‰»…‘fihydrogen sulfidej@Ø ˆ«L‚Ģ³‘Ģ
    p.74@“ńŽ_‰»’Y‘fF“ńŽ_‰»’Y‘ficarbon dioxidej@Ø ‹CŒó•Ļ“®‚Ę“K‰ž
    p.76@POPsF@Ø V‹KPOPs—LŠQ•ØŽæƒŠƒXƒg
    p.76@ƒ}ƒCƒNƒƒvƒ‰ƒXƒ`ƒbƒNF@Ø ƒ}ƒCƒNƒƒvƒ‰ƒXƒ`ƒbƒN–ā‘č
    p.76@DDTFp,p'-DDT@o,p'-DDT@Ø ŠĀ‹«ƒzƒ‹ƒ‚ƒ“‚Ę‚µ‚Ä‹^‚ķ‚ź‚Ä‚¢‚鉻‡•Ø‚Ģ—į
    p.76@PCBF3,3',4,4',5,5'-HxCBiPCB‚Ģ—įj@Ø ƒ_ƒCƒIƒLƒVƒ“—Ž
    p.76@TCDDFTCDDi2,3,7,8-TCDDj@Ø ƒ_ƒCƒIƒLƒVƒ“—Ž
    p.80@ƒrƒXƒtƒFƒm[ƒ‹AFƒrƒXƒtƒFƒm[ƒ‹Aibisphenol Aj@Ø ‘½—l‚ČƒŠƒKƒ“ƒh‚šŠÜ‚ŽƒGƒXƒgƒƒQƒ“Žó—e‘Ģ‚Ø‚ę‚ŃŠÖ˜AŽó—e‘Ģ“™‚ĢSITE”äŠr
    p.80@DEHPFƒtƒ^ƒ‹Ž_ƒrƒX(2-ƒGƒ`ƒ‹ƒwƒLƒVƒ‹)ibis(2-ethylhexyl)phthalateCDEHPj@Ø ŠĀ‹«ƒzƒ‹ƒ‚ƒ“‚Ę‚µ‚Ä‹^‚ķ‚ź‚Ä‚¢‚鉻‡•Ø‚Ģ—į
    p.80@ƒmƒjƒ‹ƒtƒFƒm[ƒ‹F4-ƒmƒjƒ‹ƒtƒFƒm[ƒ‹ip-ƒmƒjƒ‹ƒtƒFƒm[ƒ‹jk’¼½l@“Ɓk•ŖŠņŒ^‚Ģ—įl@Ø ŠĀ‹«ƒzƒ‹ƒ‚ƒ“‚Ę‚µ‚Ä‹^‚ķ‚ź‚Ä‚¢‚鉻‡•Ø‚Ģ—į
    p.86@ƒjƒgƒƒQƒi[ƒ[F1n2ciƒjƒgƒƒQƒi[ƒ[j@Ø ’‚‘f‚©‚ēŒ©‚鐶–½‚Ģ¢ŠE
    p.86@ƒŒƒOƒwƒ‚ƒOƒƒrƒ“F1bin‚ĢChain A iƒŒƒOƒwƒ‚ƒOƒƒrƒ“Aj@Ø ƒwƒ‚ƒOƒƒrƒ“
    p.84@Ž_‘fFŽ_‘f•ŖŽqidioxygenj@Ø
    p.88@”M…•¬oEF@Ø ¶–½‚š’m‚萶–½‚ÉŠw‚Ōi¶–½’a¶‚Ł‚©j
    p.93@ƒ`ƒ…[ƒuƒ[ƒ€iƒnƒIƒŠƒ€ƒVjF1yhuiƒ`ƒ…[ƒuƒ[ƒ€—R—ˆƒwƒ‚ƒOƒƒrƒ“j@Ø ƒwƒ‚ƒOƒƒrƒ“bƒ`ƒ…[ƒuƒ[ƒ€ŠÖ˜Aƒf[ƒ^‚ĢSITE—į
    p.93@ƒXƒP[ƒŠ[ƒtƒbƒgF@Ø JmolƒgƒsƒbƒN@¦ƒuƒ‹[ƒoƒbƒNƒXŠ‰ī•¶‚Ɂg“S‚Ģˆß‚Ģ³‘Ģ‚ĶA“S‚Ę—°‰©‚Ģ‰»‡•Ø‚Å‚ ‚éƒpƒCƒ‰ƒCƒg‚ĘƒOƒŒƒCƒWƒƒƒCƒgBƒOƒŒƒCƒWƒƒƒCƒg‚ĶŽ„«‚šŽ‚Ā‚½‚߁AƒXƒP[ƒŠ[ƒtƒbƒg‚ĶŽ„Ī‚É‹z‚¢Šń‚¹‚ē‚ź‚éh‚Ę‚ ‚č—¼Œ‹»\‘¢‰ę‘œ—į‚šˆČ‰ŗ‚É
    p.100@ƒuƒtƒ@ƒWƒGƒmƒ‰ƒCƒhF@Ø ƒuƒtƒ@ƒWƒGƒmƒ‰ƒCƒhibufadienolidej

    iˆČ‰ŗC”Œć’Ē‰Į‚µ‚Ü‚·j

      
    ƒtƒO“ŃeƒgƒƒhƒgƒLƒVƒ“itetrodotoxinCTTXj‚Ę‚»‚Ģģ—p‹@˜–ĶŽ®}

    ƒeƒgƒƒhƒgƒLƒVƒ“‚ŖŒ‹‡‚µ‚½“dˆŹˆĖ‘¶«ƒiƒgƒŠƒEƒ€ƒ`ƒƒƒlƒ‹6j8j‚Ę‚»‚ĢPDBsumƒf[ƒ^

          
    ¶‚©‚ē ƒjƒRƒ`ƒ“CƒAƒRƒjƒ`ƒ“CƒXƒgƒŠƒLƒj[ƒlCƒRƒ‹ƒqƒ`ƒ“

          
    ¶‚©‚ē ƒoƒgƒ‰ƒRƒgƒLƒVƒ“iBTXjCƒTƒ}ƒ“ƒ_ƒŠƒ“CƒJƒ“ƒ^ƒŠƒWƒ“Cƒzƒ‚ƒoƒgƒ‰ƒRƒgƒLƒVƒ“

      
    ¶‚©‚ē ƒ}ƒCƒgƒgƒLƒVƒ“Cƒ\ƒ‰ƒjƒ“


    1omg‚ĢModel 1iƒÖ-ƒRƒmƒgƒLƒVƒ“ MVIIAj


    ƒIƒjƒ_ƒ‹ƒ}ƒIƒRƒ[‚Ģ“Ő¬•ŖƒXƒgƒiƒXƒgƒLƒVƒ“istonustoxinCSNTXrj4wvm

      
    ƒAƒtƒ‰ƒgƒLƒVƒ“B1iaflatoxin B1j‚Ę“Æ•ŖŽq‘ćŽÓ•Ø‚ĢDNA‚Ö‚ĢCüi1ag5‚Ģ•”•Ŗ\‘¢j

      
    ƒfƒIƒLƒVƒjƒoƒŒƒm[ƒ‹ideoxynivalenolj‚Ę“Æ•ŖŽqŒ‹‡PDBsumƒf[ƒ^—įiŌƒJƒr•a‹Ū‚Ģ3-O-ƒAƒZƒ`ƒ‹ƒgƒ‰ƒ“ƒXƒtƒFƒ‰[ƒ[3b2sj

        
    ¶‚©‚ē ƒCƒ{ƒeƒ“Ž_Cƒ€ƒVƒ‚[ƒ‹Cƒ€ƒXƒJƒŠƒ“

        
    ¶‚©‚ē ƒVƒƒVƒrƒ“CƒVƒƒVƒ“CƒRƒvƒŠƒ“

      
    m¶nƒæ-ƒAƒ}ƒjƒ`ƒ“iƒAƒ}ƒgƒLƒVƒ“—Ž‚Ģ—įj@m’†E‰EnDNAERNA‚Ęƒæ-ƒAƒ}ƒjƒ`ƒ“‚ŖŒ‹‡‚µ‚½RNAƒ|ƒŠƒƒ‰[ƒ[II 6exv‚ĢChain AEMENEPET‚Ę‚»‚ĢPDBsumƒf[ƒ^

      
    m¶nƒ^ƒ}ƒSƒeƒ“ƒOƒ^ƒP’†“Å‚Ģ‰š“ÅÜ‚Ę–Ś‚³‚ź‚éƒCƒ“ƒhƒVƒAƒjƒ“ƒOƒŠ[ƒ“iICGj
    m’†E‰EnNature CommunicationsŽ˜_•¶‚Ńo[ƒ`ƒƒƒ‹ƒXƒNƒŠ[ƒjƒ“ƒO‚É—p‚¢‚ē‚ź‚½PDB 6S7TiSTT3Bƒ^ƒ“ƒpƒNŽæj‚ĢPDBsumƒf[ƒ^iICGŒ‹‡ŠY“–•”ˆŹj‚Ę“Æ˜_•¶Fig. 4eiICG‚ĢLigPlot+}j

      
    m¶n‰–‰»ƒƒ`ƒ‹…‹āimethylmercury chloridej@m‰Enƒ_ƒCƒIƒLƒVƒ“—Ž‚Ģ2,3,7,8-TCDDE2,3,7,8-TCDFE3,3',4,4',5-PeCB‚Ģ“ÆŽž•\Ž¦

        
    m¶nƒjƒgƒƒQƒi[ƒ[‚Ģ\‘¢—į1n2ciAzotobacter vinelandii—R—ˆj
    m’†nƒqƒg—R—ˆƒwƒ‚ƒOƒƒrƒ“A 2hhb‚Ę‘å“¤—R—ˆƒŒƒOƒwƒ‚ƒOƒƒrƒ“A 1bin‚Ģ”äŠri‰½‚ź‚ąChain Aj
    m‰Enƒ`ƒ…[ƒuƒ[ƒ€—R—ˆƒwƒ‚ƒOƒƒrƒ“1yhui24—Ź‘Ģj‚Ęƒqƒg‚Ģƒwƒ‚ƒOƒƒrƒ“1hhoiƒIƒLƒVƒwƒ‚ƒOƒƒrƒ“C4—Ź‘Ģj‚Ģ‘å‚«‚³”ä‚×

      
    m¶nƒpƒCƒ‰ƒCƒgipyriteC‰©“Szj‚ĢŒ‹»‚Ę‚»‚Ģģćƒ‚ƒfƒ‹‚É‚ę‚é\‘¢—į
    m‰EnAmerican Mineralogist Crystal Structure Database‚É‚ę‚éƒOƒŒƒCƒWƒƒƒCƒgigreigitej‚ĢŒ‹»\‘¢—įiJSmol‚É‚ę‚éj


    ƒuƒtƒ@ƒWƒGƒmƒ‰ƒCƒhibufadienolidej


  4. Structural basis for bacterial energy extraction from atmospheric hydrogeniNatureC2023/03/08j [NEW!]@¦2023/01/04ŒöŠJ7utdE7uurE7uusE8dqvi‰ŗŒfj

    [NiFe]-ƒqƒhƒƒQƒi[ƒ[ Huc 8dqv‚ĢChain AEB
    mNiFe hydrogenase - Wikipedian
    8dqv‚ĢChain AEBi[NiFe]-ƒqƒhƒƒQƒi[ƒ[ Hucj@“ÆPDBsumƒf[ƒ^8dqv_FCO-Ni[603(A)]iNi[604(A)]’Ē‰Įj$@“ÆPDBsumƒf[ƒ^8dqv_F3S[402(B)]$

    ƒoƒbƒNƒ{[ƒ“@“ńŽŸ\‘¢
    ‘S‘I‘š@ƒ^ƒ“ƒpƒNŽæ‘I‘š@ƒŠƒKƒ“ƒh‘I‘š@HB‘I‘ši$ˆó‚Ģ‚Żj
    ‹óŠŌ[“U@‹…–_@‹…60“@ƒXƒeƒBƒbƒN@j‹ą@Į‹Ž
    ƒAƒ~ƒmF@ChainF@CPKF@a@JmolF@RasmolF

    Ž_«E’†«E‰–Šī«‹ę•Ź@‹É«E”ń‹É«‹ę•Ź
    ‘a…«ƒCƒ“ƒfƒbƒNƒX‡@I/O’l‡i“Į«Šī Rj@“™“d“_‡
    ƒRƒ“ƒzƒ[ƒVƒ‡ƒ“‘I‘š«iƒæƒwƒŠƒbƒNƒXEƒĄƒXƒgƒ‰ƒ“ƒhj
    …‘fŒ‹‡•\Ž¦
    @
    @@
    ”wŒiE•@ŠD@”’@®


    [NiFe]-ƒqƒhƒƒQƒi[ƒ[ Huc 8dqv‚ĢChain AEB‚Ę‚»‚ĢPDBsumƒf[ƒ^iˆźŽ_‰»’Y‘f-(ƒWƒVƒAƒm)“S{Ni3+‚Ø‚ę‚ŃFE3-S4ƒNƒ‰ƒXƒ^[j


  5. The structure of AgamOBP5 in complex with the natural insect repellents Carvacrol and Thymol: Crystallographic, fluorescence and thermodynamic binding studiesiInternational Journal of Biological MacromoleculesC202/15j [NEW!]@¦2023/03/22ŒöŠJ8bxwi‰ŗŒfj

    ƒJƒ‹ƒoƒNƒ[ƒ‹icarvacrolj‚ŖŒ‹‡‚µ‚½“õ‚¢•ŖŽqŒ‹‡ƒ^ƒ“ƒpƒNŽæAgamOBP5 8bxw
    iDL‚Å‚«‚écifƒf[ƒ^‚ĢChain AAA‚šChain A‚ɏ‘‚«Š·‚¦CcifØpdbƒf[ƒ^•ĻŠ·j
    mOdorant-binding protein - Wikipedian
    8bxwiƒJƒ‹ƒoƒNƒ[ƒ‹qcarvacrolr‚ŖŒ‹‡‚µ‚½“õ‚¢•ŖŽqŒ‹‡ƒ^ƒ“ƒpƒNŽæAgamOBP5j@S5ViƒJƒ‹ƒoƒNƒ[ƒ‹j‘I‘š@“ÆPDBsumƒf[ƒ^8bxw_lp[305(AAA)]iƒJƒ‹ƒoƒNƒ[ƒ‹j$

    ƒoƒbƒNƒ{[ƒ“@“ńŽŸ\‘¢
    ‘S‘I‘š@ƒ^ƒ“ƒpƒNŽæ‘I‘š@ƒŠƒKƒ“ƒh‘I‘š@HB‘I‘ši$ˆó‚Ģ‚Żj
    ‹óŠŌ[“U@‹…–_@‹…60“@ƒXƒeƒBƒbƒN@j‹ą@Į‹Ž
    ƒAƒ~ƒmF@ChainF@CPKF@a@JmolF@RasmolF

    Ž_«E’†«E‰–Šī«‹ę•Ź@‹É«E”ń‹É«‹ę•Ź
    ‘a…«ƒCƒ“ƒfƒbƒNƒX‡@I/O’l‡i“Į«Šī Rj@“™“d“_‡
    ƒRƒ“ƒzƒ[ƒVƒ‡ƒ“‘I‘š«iƒæƒwƒŠƒbƒNƒXEƒĄƒXƒgƒ‰ƒ“ƒhj
    …‘fŒ‹‡•\Ž¦
    @
    @@
    ”wŒiE•@ŠD@”’@®


    ƒJƒ‹ƒoƒNƒ[ƒ‹qcarvacrolr‚ŖŒ‹‡‚µ‚½“õ‚¢•ŖŽqŒ‹‡ƒ^ƒ“ƒpƒNŽæAgamOBP5 8bxw‚Ę‚»‚ĢPDBsumƒf[ƒ^
    ¦DL‚Å‚«‚écifƒf[ƒ^‚ĢChain AAA‚šChain A‚ɏ‘‚«Š·‚¦CcifØpdbƒf[ƒ^•ĻŠ·


  6. Small molecule inhibitors of 15-PGDH exploit a physiologic induced-fit closing systemiNature CommunicationsC2023/02/11j [NEW!]@¦2023/03/01ŒöŠJ8cvni‰ŗŒfjE8cwlE8fd8

    ‘jŠQÜSW209415‚ŖŒ‹‡‚µ‚½15-ƒqƒhƒƒLƒVƒvƒƒXƒ^ƒOƒ‰ƒ“ƒWƒ“ƒfƒqƒhƒƒQƒi[ƒ[i15-PGDHj 8cvn‚ĢChain A
    m15-hydroxyprostaglandin dehydrogenase (NAD+) - Wikipedian
    8cvn‚ĢChain Ai‘jŠQÜSW209415‚ŖŒ‹‡‚µ‚½15-ƒqƒhƒƒLƒVƒvƒƒXƒ^ƒOƒ‰ƒ“ƒWƒ“ƒfƒqƒhƒƒQƒi[ƒ[q15-PGDHrj@SWLiSW209415j‘I‘š@“ÆPDBsumƒf[ƒ^8cvn_SWL$ b PDBsumƒf[ƒ^8cwl_RLDi‘jŠQÜSW222746j$@RLDiSW222746j‘I‘š
    ƒoƒbƒNƒ{[ƒ“@“ńŽŸ\‘¢
    ‘S‘I‘š@ƒ^ƒ“ƒpƒNŽæ‘I‘š@ƒŠƒKƒ“ƒh‘I‘š@HB‘I‘ši$ˆó‚Ģ‚Żj
    ‹óŠŌ[“U@‹…–_@‹…60“@ƒXƒeƒBƒbƒN@j‹ą@Į‹Ž
    ƒAƒ~ƒmF@ChainF@CPKF@a@JmolF@RasmolF

    Ž_«E’†«E‰–Šī«‹ę•Ź@‹É«E”ń‹É«‹ę•Ź
    ‘a…«ƒCƒ“ƒfƒbƒNƒX‡@I/O’l‡i“Į«Šī Rj@“™“d“_‡
    ƒRƒ“ƒzƒ[ƒVƒ‡ƒ“‘I‘š«iƒæƒwƒŠƒbƒNƒXEƒĄƒXƒgƒ‰ƒ“ƒhj
    …‘fŒ‹‡•\Ž¦
    @
    @@
    ”wŒiE•@ŠD@”’@®


    ‘jŠQÜSW209415‚ŖŒ‹‡‚µ‚½15-ƒqƒhƒƒLƒVƒvƒƒXƒ^ƒOƒ‰ƒ“ƒWƒ“ƒfƒqƒhƒƒQƒi[ƒ[i15-PGDHj 8cvn‚ĢChain A‚Ę‚»‚ĢPDBsumƒf[ƒ^i‘jŠQÜSW222746Œ‹‡‚Ģ8cwl‚Ę‚Ģ”äŠrj


  7. ˆź‰Ę‚É1–‡b‰ČŠw‹ZpTŠŌ SCIENCE & TECHNOLOGY WEEK@¦2023”Nwˆź‰Ę‚É1–‡ ƒEƒCƒ‹ƒXxŒöŠJi‰ŗ}j


    wˆź‰Ę‚É1–‡ ƒEƒCƒ‹ƒXx
    ‚©‚ē

    PDBƒf[ƒ^ 3cl0iƒIƒZƒ‹ƒ^ƒ~ƒrƒ‹qoseltamivirG¤•i–¼ƒ^ƒ~ƒtƒ‹r‚Ģ‘ćŽÓŠˆ«‘ĢGS4071‚ŖŒ‹‡‚µ‚½’¹ƒCƒ“ƒtƒ‹ƒGƒ“ƒUƒEƒCƒ‹ƒX‚ĢN1ƒmƒCƒ‰ƒ~ƒjƒ_[ƒ[j

    ƒCƒ“ƒtƒ‹ƒGƒ“ƒUƒEƒCƒ‹ƒXF3cl0iƒIƒZƒ‹ƒ^ƒ~ƒrƒ‹qoseltamivirG¤•i–¼ƒ^ƒ~ƒtƒ‹r‚Ģ‘ćŽÓŠˆ«‘ĢGS4071‚ŖŒ‹‡‚µ‚½’¹ƒCƒ“ƒtƒ‹ƒGƒ“ƒUƒEƒCƒ‹ƒX‚ĢN1ƒmƒCƒ‰ƒ~ƒjƒ_[ƒ[j@Ø ’¹ƒCƒ“ƒtƒ‹ƒGƒ“ƒU•VŒ^ƒCƒ“ƒtƒ‹ƒGƒ“ƒUī•ń
    ƒRƒƒiƒEƒCƒ‹ƒXF1q2w‚ĢChain AiSARSƒRƒƒiƒEƒCƒ‹ƒX‚ĢƒvƒƒeƒA[ƒ[j@Ø SARS‚ʍRƒEƒCƒ‹ƒX–ņ b 6lu7‚Ģ4—Ź‘ĢiChain AEC~2GVŒ^ƒRƒƒiƒEƒCƒ‹ƒXSARS-CoV-2‚ĢŽå—vƒvƒƒeƒA[ƒ[j@Ø VŒ^ƒRƒƒiƒEƒCƒ‹ƒXiSARS-CoV-2bCOVID-19jī•ń
    RSƒEƒCƒ‹ƒXF5ea3i‘jŠQÜJNJ-2408068‚ŖŒ‹‡‚µ‚½RSƒEƒCƒ‹ƒX‚ĢF“œƒ^ƒ“ƒpƒNŽæj@Ø JmolƒgƒsƒbƒN
    ƒ‰ƒCƒmƒEƒCƒ‹ƒXF1aym‚Ģ20—Ź‘Ģiƒ‰ƒCƒmƒEƒCƒ‹ƒXGChain 1-4 ~ 5j@Ø ¶‘Ģ•ŖŽq‚Ķ‘ĪĢŒ`‚Ŗ‚؍D‚«H
    Fij@Ø
    Fij@Ø
    Fij@Ø
    Fij@Ø
    Fij@Ø

    i”Œć‚ą’Ē‰Į‚µ‚Ü‚·j

    ƒoƒbƒNƒ{[ƒ“@“ńŽŸ\‘¢
    ‘S‘I‘š@ƒ^ƒ“ƒpƒNŽæ‘I‘š@ƒŠƒKƒ“ƒh‘I‘š@
    ‹óŠŌ[“U@‹…–_@‹…60“@ƒXƒeƒBƒbƒN@j‹ą@Į‹Ž
    ƒAƒ~ƒmF@ChainF@CPKF@a@JmolF@RasmolF

    Ž_«E’†«E‰–Šī«‹ę•Ź@‹É«E”ń‹É«‹ę•Ź
    ‘a…«ƒCƒ“ƒfƒbƒNƒX‡@I/O’l‡i“Į«Šī Rj@“™“d“_‡
    ƒRƒ“ƒzƒ[ƒVƒ‡ƒ“‘I‘š«iƒæƒwƒŠƒbƒNƒXEƒĄƒXƒgƒ‰ƒ“ƒhj
    …‘fŒ‹‡•\Ž¦
    @
    @@
    ”wŒiE•@ŠD@”’@®

      
    m¶nƒCƒ“ƒtƒ‹ƒGƒ“ƒUƒEƒCƒ‹ƒX‚Ģ\‘¢GƒTƒuƒ^ƒCƒvwH?N?x‚šŒˆ‚ß‚é‚Ģ‚Ŗƒwƒ}ƒOƒ‹ƒ`ƒjƒ“iHAGH1`H16j‚ĘƒmƒCƒ‰ƒ~ƒjƒ_[ƒ[iNAGN1`N9j
    m‰EnƒIƒZƒ‹ƒ^ƒ~ƒrƒ‹ioseltamivirG¤•i–¼ƒ^ƒ~ƒtƒ‹j‚Ģ‘ćŽÓŠˆ«‘ĢGS4071‚ŖŒ‹‡‚µ‚½’¹ƒCƒ“ƒtƒ‹ƒGƒ“ƒUƒEƒCƒ‹ƒX‚ĢN1ƒmƒCƒ‰ƒ~ƒjƒ_[ƒ[3cl0

      
    m¶nSARSƒRƒƒiƒEƒCƒ‹ƒX‚ĢƒvƒƒeƒA[ƒ[1q2w‚ĢChain A
    m‰EnVŒ^ƒRƒƒiƒEƒCƒ‹ƒXSARS-CoV-2‚ĢƒvƒƒeƒA[ƒ[6lu7‚Ģ4—Ź‘ĢiChain AEC~2j


    ‘jŠQÜJNJ-2408068‚ŖŒ‹‡‚µ‚½RSƒEƒCƒ‹ƒX‚ĢF“œƒ^ƒ“ƒpƒNŽæ5ea3


  8. ”ŒŽ‚Ģ•ŖŽq 280:ŒćŠś‘£i•”‡‘Ģ/ƒTƒCƒNƒƒ\[ƒ€iAnaphase-Promoting Complex / CyclosomejiPDBjC2023/04j [NEW!] b Molecule of the MonthiPDBj

    Žå—v‘gD“K‡«•”‡‘ĢIiMHC Ij-ƒyƒvƒ`ƒhƒ[ƒfƒBƒ“ƒO•”‡‘ĢiPLCj7qpd
    mMHC class I - WikipediaCPeptide loading complex - Wikipedian
    ƒoƒbƒNƒ{[ƒ“@“ńŽŸ\‘¢
    ‘S‘I‘š@ƒ^ƒ“ƒpƒNŽæ‘I‘š@ƒŠƒKƒ“ƒh‘I‘š@HB‘I‘ši$ˆó‚Ģ‚Żj
    ‹óŠŌ[“U@‹…–_@‹…60“@ƒXƒeƒBƒbƒN@j‹ą@Į‹Ž
    ƒAƒ~ƒmF@ChainF@CPKF@a@JmolF@RasmolF

    “œ½•Ź’…Fi#ˆó‚Ģ‚ŻjFGalCƒæ-GlcCƒĄ-GlcCManCFucCXylCSiaCGalNAcCGlcNAcCGlcA
    Ž_«E’†«E‰–Šī«‹ę•Ź@‹É«E”ń‹É«‹ę•Ź
    ‘a…«ƒCƒ“ƒfƒbƒNƒX‡@I/O’l‡i“Į«Šī Rj@“™“d“_‡
    ƒRƒ“ƒzƒ[ƒVƒ‡ƒ“‘I‘š«iƒæƒwƒŠƒbƒNƒXEƒĄƒXƒgƒ‰ƒ“ƒhj
    …‘fŒ‹‡•\Ž¦
    @
    @@
    ”wŒiE•@ŠD@”’@®


    Žå—v‘gD“K‡«•”‡‘ĢIiMHC Ij-ƒyƒvƒ`ƒhƒ[ƒfƒBƒ“ƒO•”‡‘ĢiPLCj‚Ģ\‘¢7qpd


  9. Recognition Mechanism of a Novel Gabapentinoid Drug, Mirogabalin, for Recombinant Human ƒæ2ƒĀ1, a Voltage-Gated Calcium Channel SubunitiJournal of Molecular BiologyC2023/03/15j [NEW!]@¦2023/04/06ŒöŠJ8if3i‰ŗŒfjE8if4

    ƒ~ƒƒKƒoƒŠƒ“imirogabalinj‚ŖŒ‹‡‚µ‚½Na-Cl‹¤—A‘—‘Ģ8if3
    mVoltage-dependent calcium channel - WikipediaCMirogabalin - Wikipedian
    8if3iƒ~ƒƒKƒoƒŠƒ“qmirogabalinr‚ŖŒ‹‡‚µ‚½Na-Cl‹¤—A‘—‘Ģj@“ÆPDBsumƒf[ƒ^8if3_lp$
    ƒoƒbƒNƒ{[ƒ“@“ńŽŸ\‘¢
    ‘S‘I‘š@ƒ^ƒ“ƒpƒNŽæ‘I‘š@ƒŠƒKƒ“ƒh‘I‘š@HB‘I‘ši$ˆó‚Ģ‚Żj
    ‹óŠŌ[“U@‹…–_@‹…60“@ƒXƒeƒBƒbƒN@j‹ą@Į‹Ž
    ƒAƒ~ƒmF@ChainF@CPKF@a@JmolF@RasmolF

    “œ½•Ź’…Fi#ˆó‚Ģ‚ŻjFGalCƒæ-GlcCƒĄ-GlcCManCFucCXylCSiaCGalNAcCGlcNAcCGlcA
    Ž_«E’†«E‰–Šī«‹ę•Ź@‹É«E”ń‹É«‹ę•Ź
    ‘a…«ƒCƒ“ƒfƒbƒNƒX‡@I/O’l‡i“Į«Šī Rj@“™“d“_‡
    ƒRƒ“ƒzƒ[ƒVƒ‡ƒ“‘I‘š«iƒæƒwƒŠƒbƒNƒXEƒĄƒXƒgƒ‰ƒ“ƒhj
    …‘fŒ‹‡•\Ž¦
    @
    @@
    ”wŒiE•@ŠD@”’@®


    ƒ~ƒƒKƒoƒŠƒ“imirogabalinj‚ŖŒ‹‡‚µ‚½Na-Cl‹¤—A‘—‘Ģ8if3‚Ę‚»‚ĢPDBsumƒf[ƒ^


  10. XüŽ©—R“dŽqƒŒ[ƒU[‚Å‘Ø‚¦‚½ƒrƒtƒBƒYƒX‹Ūy‘f‚Ģķ‰·\‘¢ |‹ĒŠ“I‚ȍ\‘¢•Ļ‰»‚©‚ēŽ¦“‚³‚ź‚½y‘f”½‰žƒƒJƒjƒYƒ€|iSPring-8C2023/04/10j [NEW!]

    ƒ`ƒAƒ~ƒ““ńƒŠƒ“Ž_CƒzƒXƒzƒGƒm[ƒ‹ƒsƒ‹ƒrƒ“Ž_‚ŖŒ‹‡‚µ‚½ƒzƒXƒzƒPƒgƒ‰[ƒ[7c8i‚ĢChain AEB
    mPhosphoketolase - WikipediaCThiamine pyrophosphate - WikipediaCPhosphoenolpyruvic acid - Wikipedian
    7c8i‚ĢChain AEBiƒ`ƒAƒ~ƒ““ńƒŠƒ“Ž_CƒzƒXƒzƒGƒm[ƒ‹ƒsƒ‹ƒrƒ“Ž_‚ŖŒ‹‡‚µ‚½ƒzƒXƒzƒPƒgƒ‰[ƒ[j@ŽcŠī”Ō†546-549‹…–_•\Ž¦^ƒæ’Y‘fƒ‰ƒxƒ‹•\Ž¦@“ÆPDBsumƒf[ƒ^7c8i_TPP$@“ÆPDBsumƒf[ƒ^7c8i_PEP$
    ƒoƒbƒNƒ{[ƒ“@“ńŽŸ\‘¢
    ‘S‘I‘š@ƒ^ƒ“ƒpƒNŽæ‘I‘š@ƒŠƒKƒ“ƒh‘I‘š@HB‘I‘ši$ˆó‚Ģ‚Żj
    ‹óŠŌ[“U@‹…–_@‹…60“@ƒXƒeƒBƒbƒN@j‹ą@Į‹Ž
    ƒAƒ~ƒmF@ChainF@CPKF@a@JmolF@RasmolF

    Ž_«E’†«E‰–Šī«‹ę•Ź@‹É«E”ń‹É«‹ę•Ź
    ‘a…«ƒCƒ“ƒfƒbƒNƒX‡@I/O’l‡i“Į«Šī Rj@“™“d“_‡
    ƒRƒ“ƒzƒ[ƒVƒ‡ƒ“‘I‘š«iƒæƒwƒŠƒbƒNƒXEƒĄƒXƒgƒ‰ƒ“ƒhj
    …‘fŒ‹‡•\Ž¦
    @
    @@
    ”wŒiE•@ŠD@”’@®


    ƒ`ƒAƒ~ƒ““ńƒŠƒ“Ž_CƒzƒXƒzƒGƒm[ƒ‹ƒsƒ‹ƒrƒ“Ž_‚ŖŒ‹‡‚µ‚½ƒzƒXƒzƒPƒgƒ‰[ƒ[iphosphoketolasej7c8i‚ĢChain AEB‚Ę‚»‚ĢPDBsumƒf[ƒ^
    ¦žņF‹…–_•\Ž¦‚Ķ˜_•¶’†‚ĢgGln546-Asp547-His548-Asn549 (the QN-loop)h


u¶ŠˆŠĀ‹«‰»Šw‚Ģ•”‰®vƒz[ƒ€ƒy[ƒW b Jmol”Łu•ŖŽq‚ĢŠwK’ v